In adaptation, a vigorous early response gives way to little or no chronic response. The output is determined by changes in the input rather than the magnitude of the input.
In the figure above, the input is a step function of amplitude 1 that occurs at time equal to 4 (Red). The output is initially equal to the input, but then it decays toward 0 as time passes (Blue).
Since many biological processes adapt, this can be a useful tool to have in your toolbox.
The equations for this model are
dA/dt = K * Output
Output = Input - A
A is the adaptation term, shown in the figure above (Magenta).
K is the adaptation rate constant. The adaptation time constant (Tau) is the reciprocal of the rate constant.
Tau = 1 / K
For a step change in input, when time = Tau, Output = 0.63 * Input.
The adaptation half-time is the time required for the output to fall to one-half of its initial value.
t 1/2 = 0.69 * Tau
Right click here to download Adaptation 2005.DES (See note below for download instructions)
A Note On Downloads. If you left click on the link above, your browser will probably fail to download the file but instead will try to display the file when it sees the file's XML content. So right click on the link instead and then select Save Target As...in explorer or Save Link Target as... in Netscape and Mozilla in the context menu.
updated 03-02-05