Selected Publications of Suresh C. Tyagi, Ph.D.


Tummalapalli CM, Heath BJ, Tyagi SC. Tissue inhibitor of metalloproteinase-4 instigates apoptosis in transformed cardiac fibroblasts, J Cell Biochem, 2001;80(4):512-521.

Henegar JR, Bigler SA, Henegar LK, Tyagi SC, Hall JE. Functional and structural changes in the kidney in the early stages of obesity, J Am Soc Nephrol, 2001, 12:1211-1217.

Mujumdar VS, Aru GM, Tyagi SC. Induction of oxidative stress by homocyst(e)ine impairs endothelial function, J Cell Biochem, 2001; 82(3):491-500.

Mujumdar VS, Smiley LM, Tyagi SC. Activation of matrix metalloproteinase dilates and decreases cardiac tensile strength, Intern J Cardiol, 2001;79(2-3):277-286.

Mujumdar VS, Hayden MR, Tyagi SC (2000) Homocysteine induces calcium secondary messenger in vascular smooth muscle cells, J Cell Physiol, 183:28-36.

Miller A, Mujumdar V, Shek E, Guillot J, Angelo M, Pakmer L, Tyagi SC. Hyperhomo-cysteinemia induces multiorgan damage, Heart and Vessels, 2000;15(3):135-143.

Mujumdar VS, Tyagi SC (1999) Temporal Regulation of Extracellular Matrix Components in Transition from Compensatory Hypertrophy to Decompensatory Heart Failure, J Hypertension, 17, 261-270.

Tummalapalli CM, Tyagi SC (1999) Response of vascular smooth muscle cells to extracellular matrix degradation, J Cell Biochem, 75:515-527.

Tyagi SC, Smiley LM, Mujumdar VS (1999) Homocyst(e)ine impairs endocardial endothelial function, Canad J Physiol & Pharmacology, 77:950-957.

Tyagi SC, Smiley LM, Mujumdar VS, Clonts B, Parker JL (1998) Reduction-oxidation (redox) and vascular tissue level of homocyst(e)ine in human coronary atherosclerotic lesions and role in vascular extracellular matrix remodeling and vascular tone, Mol Cell Biochem, 181, 107-116.

Johnson PJ, Tyagi SC, Katwa LC, Ganjam VK, Moore LA, Kreeger JM, Messer NT, 1998, Activation of extracellular matrix metalloproteinases in equine laminitis, Veterinary Record, 142, 392-396.

Katwa LC, Sun Y, Campbell SE, Tyagi SC, Dhalla AK, Kandala JC, Weber KT (1998) Pouch tissue and angiotensin peptide generation, J Mol Cell Cardiol, 30, 1401-1413.

Tyagi SC, Lewis K, Pikes D, Marcello A, Mujumdar V, Smiley L, Moore CK (1998) Stretch induced membrane type matrix metalloproteinases and tissue plasminogen activator in cardiac fibroblast cells, J Cell Physiol, 176, 374-382.

Tyagi SC (1998) Homocysteine redox receptor and regulation of extracellular matrix components in vascular cells, Am J Physiol, 274, C396-C405.

Tyagi SC, Kumar S & Katwa L (1997) Differential regulation of extracellular matrix metalloproteinase and tissue inhibitor by heparin and cholesterol in fibroblast cells, J Mol Cell Cardiol, 29, 391-404.

Katwa LC, Campbell SE, Tyagi SC, Lee SJ, Cicila GT, Weber KT (1997) Cultured myofibroblasts generate angiotensin peptides de novo, J Mol Cell Cardiol, 29, 1375-1386.

Zhou G, Kandala JC, Tyagi SC, Katwa LC & Weber KT (1996) Effects of angiotensin II and aldosterone on collagen gene expression and protein turnover in cardiac fibroblasts, Mol Cell Biochem, 154, 171-178.

Katwa LC, Tyagi SC, Campbell SE, Lee SJ, Cilila GT & Weber KT (1996) Valvular interstitial cells express aspartyl protease cathepsin D, Intern J Biochem & Cell Biol, 28, 807-821.

Tyagi SC, Kumar SG & Borders S (1996) Reduction-Oxidation (Redox) State Regulation of Extracellular Matrix Metalloproteinases and Tissue Inhibitors in Cardiac Normal and Transformed Fibroblast Cells, J Cell Biochem, 61, 139-151.

Tyagi SC, Kumar SG, Alla SR, Reddy HK, Voelker DJ & Janicki JS (1996) Extracellular Matrix Regulation of Metalloproteinase and Antiproteinase in Human Heart Fibroblast Cells, J Cell Physiol, 167, 137-147.

Tyagi SC, Campbell SE, Reddy HK, Tjahja E & Voelker DJ (1996) Matrix metalloproteinase activity expression in infarcted, noninfarcted and dilated cardiomyopathic human hearts, Mol Cell Biochem, 155, 13-21.

Tyagi SC, Meyer L, Kumar SG, Schmaltz RA, Reddy HK & Voelker DJ (1996) Induction of tissue inhibitor of metalloproteinase and its mitogenic response to endothelial cells in human atherosclerotic and restenotic lesions, Canad J Cardiol, 12, 353-362.

Tyagi SC, Haas SJ, Kumar SG, Reddy HK, Voelker DJ, Hayden MR, Demmy TL, Schmaltz RA & Curtis JJ (1996) Post-trancriptional regulation of extracellulr matrix metalloproteinse in human heart end-stage failure secondary to ischemic cardiomyopathy, J Mol Cell Cardiol, 28, 1415-1428.

Tyagi SC (1996) Role of Oxidative Mixed-Disulfide Formation in Elastase-Serine Proteinase Inhibitor (Serpin) Complex, Biochem & Cell Biol, 74, 391-401. 9. Tyagi SC, Kumar SG, Cassatt S & Parker JL (1996) Temporal expression of extracellular matrix metalloproteinase and tissue plasminogen activator in the development of collateral vessels in canine model of coronary occlusion, Canad J Physiol & Pharmacol, 74, 983-995

Tyagi SC, Kumar SG, Voelker DJ, Reddy HK, Janicki JS & Curtis JJ (1996) Differntial gene expression of extracellular matrix components in dilated cardiomyopathy, J Cell Biochem, 63, 185-198.

INVITED REVIEWS AND BOOK CHAPTERS:

Tyagi SC, Bheemanathini VS, Mandi S, Reddy HK, Voelker DJ (1996) Role of extracellular matrix metalloproteinases in cardiac remodeling, Heart Failure Reviews (Goldstein S, & Sabbah HN, eds) Kluwer Academic Publishers, Boston, 1, 73-80.

Tyagi SC (1997) Proteinases and myocardial extracellular matrix turnover, Mol Cell Biochem, 168, 1-12.

Tyagi SC (1997) Vasculogenesis and angiogenesis: extracellular matrix remodeling in coronary collateral arteries and the ischemic heart, J Cell Biochem, 65, 388-395.

Tyagi SC (1997) Dynamic Extracellular Matrix Remodeling in the Heart Failure: Cardiac hypertrophy, Dilatation and Fibrosis, Pathophysiology, 4, 227-234.

Tyagi SC, Hayden MR, Hall JE (1998) Role of angiotensin in angiogenesis and cardiac fibrosis in heart failure, Angiotensin II Receptor Blockade: Physiological and Clinical Implications, (Dhalla NS, Zahradka P, Dixon IMC, Beamish RE, eds) Kluwer Academic Publishers, Boston, Progress in Experiential Cardiology, 2, 537-549.

Hayden MR, Tyagi SC (1998) Atherosclerosis: Implication of Angiotensin II and the AT-1 Receptor, Angiotensin II Receptor Blockade: Physiological and Clinical Implications, (Dhalla NS, Zahradka P, Dixon IMC, Beamish RE, eds) Kluwer Academic Publishers, Boston, Progress in Experimental Cardiology, 2, 550-555.

Tyagi SC (1998) Extracellular Matrix Dynamics in Heart Failure: A Prospect for Gene Therapy, J Cell Biochem, 68, 403-410.

Tyagi SC, 1998 Dynamic role of extracellular matrix metalloproteinases in heart failure, Cardiovasc Pathol, 7, 153-159.

Hayden MR, Tyagi SC, 1998, Arterial Vascular Remodeling: The Endothelial Cell Central Role, Missouri Medicine, 95, 213-217.

Tyagi SC (1999) Homocyst(e)ine and Heart Disease: Pathophysiology of Extracellular Matrix, Clin & Exper Hypertension, 21:181-198.

Hayden MR, Tyagi SC (2000) Remodeling of the endocrine pancreas: The central role of amylin and insulin resistance, Southern Med J, 93:24-28.

Hayden MR, Tyagi SC (2000) Arteriogenesis: Angiogenesis within unstable atherosclerotic plaque-interactions with extracellular matrix, Curr Intervent Cardiol Report, 2:218-227.

Tyagi SC. Physiology of Extracellular Matrix: Cardiovascular Adapation and Remodeling, Pathophysiology, 2000;7:177-182.

Hayden MR, Tyagi SC. "A" is for amylin and Amyloid in type 2 diabetes mellitus, J Pancreas, 2001;2(4):124-139.