Thomas Lohmeier, Ph.D.

Biographical Sketch (pdf)

Areas of Expertise

General: Cadiovascular, renal, and endocrine
Specific: Neurohormonal mechanisms in the pathogenesis of hypertension and heart failure

Research Methods and Experimental Models

Chronic instrumentation of dogs for measurement of hemodynamics and renal function. Measurement of norepinephrine kinetics for determination of whole-body and regional (especially renal) sympathetic activity. Split-bladder preparation in combination with unilateral renal denervation for assessing 24-h neural control of renal function. Fos immunohistochemistry for assessing CNS neuronal activation. Chronic electrical activation of the carotid baroreflex by electrical stimulation of the carotid sinus for determination of baroreflex functionSinoaortic and cardiopulmonary deafferentation for determination of baroreflex function