Thomas Adair, Ph.D.
Thomas Adair, Ph.D. |
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General:Cardiovascular and microcirculatory physiology. Vascular biology.
Specific: Growth regulation of the vascular system; metabolic control of angiogenesis especially role of oxygen and adenosine; modelling and computer simulation of the cardiovascular system.
Methods for studying angiogenesis both in vivo and in vitro include long-term electrical stimulation of skeletal muscle in rabbits, rats, and mice; chick embryo CAM and whole body assays; rat and mouse aortic ring angiogenesis assays; mouse left ventricular angiogenesis assay; in vivo angioreactor. Analytical methods: histology, morphometric and stereological analyses of the vasculature, immunohistochemistry, and molecular biology methods for studying proangiogenic and antiangiogenic growth factors.